Mitochondrial Function Panel - Laboratory Testing

Mitochondria are the cellular energy generators that supply virtually all the power your body requires for a healthy life. There is mounting evidence that glaucoma is a mitochondrial optic neuropathy.10

The increasing evidence shows that age-associated mitochondrial dysfunction renders optic nerve cells susceptible to glaucomatous injury by reducing the energy available for repair processes and predisposing nerve cells to programmed death (apoptosis).8

Mitochondrial dysfunction increases reactive oxygen species (ROS) production and when this overwhelms the cellular antioxidant defences, oxidative stress ensues. Oxidative stress is recognized as a common pathologic pathway in many neurodegenerative diseases, including glaucoma. There is also accumulating evidence pointing to mitochondrial dysfunction being present in some glaucoma patients. Thus oxidative stress from mitochondrial dysfunction may also play a causal role in glaucoma.11

An abundance of published studies also underscores the critical importance of the mitochondria to overall health, especially as we age.1-7 Simply put, mitochondrial dysfunction is an energy production problem and can result in many chronic degenerative orders such as glaucoma, Alzheimers, Parkinson’s disease, obesity, diabetes, cardiovascular disease and stroke.

This blood panel contains the following tests:

  • Carnitine (free and total)
  • Coenzyme Q10 (CoQ10)
  • Glucose

Sample Report

The primary function of carnitine in the body is to regulate fat burning and to help the body use stored fat as fuel. L-Carnitine is responsible for transporting fat to the powerhouse of our cells called mitochondria. Unless fat makes it to the mitochondria, it cannot be burned, no matter how much you exercise or diet!

CoQ10 is an essential factor in healthy mitochondrial function and the production of cellular energy as glucose is converted into adenosine triphosphate (ATP). Ninety-five percent of all the human body’s energy requirements is converted with the aid of CoQ10.

Do you want to extend your life? Then be good to your mitochondria!

An 8 to 12 hour fast is required for this blood test. However, drink plenty of water and take your medications as prescribed.


Sample Report

Take control of your own health with this innovative blood testing service.

  • Affordable prices
  • No insurance required or accepted
  • Nearby locations by Zip code

Testing is as easy as 1-2-3.

  1. Order here! (Not available in Maryland)
  2. Take the requisition† you’ll receive by email (or mail) to a local LabCorp Patient Service Center.
  3. Have your blood drawn at your convenience.

So is understanding your results!

  1. Your results will be sent directly to you … by mail, e-mail or fax. Or you can view them online. It’s your call.
  2. Results take 3 days to 3 weeks to receive, depending on the complexity of the blood tests ordered and your chosen method of delivery.
  3. Once you receive them, discuss them with your own doctor. You can also call 1-800-226-2370 and ask a knowledgeable Life Extension Health Advisors for help in understanding your blood test results.

*Blood testing services are available only in the continental United States and Anchorage, AK. Not available in Maryland.

†Your blood test requisition options are a LabCorp requisition form or a blood draw kit. Certain restrictions apply for residents of MA, NY, NJ, RI, and PA. Customers in MA, NY, NJ, and RI will receive a blood draw kit, and an additional local blood draw fee may be incurred. PA customers must go to LabCorp for their blood draw.

**DISCLAIMER:

The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.

Information on this page is not intended as a substitute for advice provided by a competent health care professional. You should not use this information in diagnosing or treating a health problem. No claim or opinion expressed on this web site is intended to be, nor should be construed to be, medical advice. If you are now taking any drugs, prescribed or not, or have a medical condition, please consult a competent physician who is aware of herb/drug interactions before taking any herbal supplements. The information presented herein has not been evaluated by the FDA or the Department of Health and is not intended to diagnose, prevent or treat any disease or illness.

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Related article:

Our Aging Mitochondria – Life Extension

References

  1. Biochimie. 1999 Dec;81(12):1131-2.
  2. Lancet. 1989 Mar 25;1(8639):642-5.
  3. Curr Opin Clin Nutr Metab Care. 2010 Jul;13(4):458-65.
  4. Age (Dordr). 2010 Sep;32(3):337-46.
  5. Ageing Res Rev. 2010 Jun 25.
  6. Cell Mol Life Sci. 2010 Oct;67(20):3435-47.
  7. Zhonghua Yi Xue Za Zhi (Taipei). 2001 May;64(5):259-70.
  8. Mitochondrial dysfunction and glaucoma. [J Glaucoma. 2009] - PubMed - NCBI
  9. Mitochondrial dysfunction in glaucoma and emergi... [Exp Eye Res. 2011] - PubMed - NCBI
  10. Mitochondrial Dysfunction in Glaucoma—Closing the Loop
  11. Oxidative stress and mitochondrial dysfunction in glaucoma

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