Bone Strength Formula with KoAct 120 caps by Life Extension

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The use of diets high in collagen to improve bone health dates back to ancient cultures. Life Extension brings you this exciting formulation with KoAct®, a patented chelated form of calcium and collagen designed to maintain optimal bone health. KoAct® helps maintain bone strength and mineral density.1 This remarkable ingredient allows for greater strength and flexibility, so your bones can absorb energy, reducing the risk of age-related injuries. Additional plant extracts from bamboo and dried plum have also been added for their bone-protective minerals and polyphenols.2-8

Bone Strength Formula with KoAct® contains the following ingredients:

Vitamin D3

  • Facilitates absorption of calcium into the bloodstream.
  • Regulates how much calcium enters and leaves bone tissue.
  • Helps regulate healthy cell division and differentiation.
  • Functions as a vital co-factor in bone mineralization through the absorption of calcium and phosphorus.

Calcium

KoAct® is a unique patented chelated compound of calcium and hydrolyzed collagen peptides (type I collagen) designed to enhance collagen support and turnover while supporting optimal bone mineral density and strength,

Magnesium

  • A critical component of our skeleton, with 50-60% of totally body magnesium found in bone
  • Positively influences the bone mineral matrix and its ability to metabolize minerals needed for repair and rebuilding.

Silicon

Plays an important role in bone formation through the synthesis and/or stabilization of collagen.

Dried Plum

Supports osteoblast (bone building cells) activity and function by upregulating cell-signaling compounds (Runx2, Osterix and IGF-1) and enhancing expression of an enzyme (lysyl oxidase) that is involved in collagen cross-linking.

Boron

Impacts steroid hormone metabolism-affecting the levels of estrogens and testosterone.

If you need extra bone support, ask your healthcare professional how Bone Strength Formula with KoAct® can be part of a comprehensive nutritional program in conjunction with proper resistance exercise.

Bone Strength Formula with KoAct®

120 vegetarian capsules

Item Catalog Number: 01725

Suggested Use

Take four (4) capsules daily in divided doses with or without food, or as directed by a qualified health care professional.

 

Supplement Facts
Serving Size: 4 Capsules
Servings Per Container: 30
  Amount Per Serving % Daily Value
Vitamin D3 (as cholecalciferol) 1000 IU 250%
Calcium (from 3000 mg KoAct Calcium Collagen Chelate and calcium fructoborate) 300 mg 30%
Magnesium (as magnesium citrate) 100 mg 25%
Silicon [from standardized Bamboo (Bambusa vulgaris) extract (stem)] 5 mg **
Dried Plum (Prunus domestica) extract (fruit) [standardized to 50% polyphenols by UV-Vis (50 mg)] 100 mg **
Boron (calcium fructoborate as patented Fruitex B OsteoBoron) 3 mg **
**Daily Value not established.
Other Ingredients

Vegetable cellulose (capsule), vegetable stearate, maltodextrin, corn starch.

Warnings

Sealed for your protection.

  • Keep out of reach of children.
  • Do not exceed recommended dose.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
**DISCLAIMER: Information on this page is not intended as a substitute for advice provided by a competent health care professional. You should not use this information in diagnosing or treating a health problem. No claim or opinion expressed on this web site is intended to be, nor should be construed to be, medical advice. If you are now taking any drugs, prescribed or not, or have a medical condition, please consult a competent physician who is aware of herb/drug interactions before taking any herbal supplements. The information presented herein has not been evaluated by the FDA or the Department of Health and is not intended to diagnose, prevent or treat any disease or illness.

 

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References

1. Hooshmand S et al. Evidence for bone reversal properties of a calcium-collagen chelate, a novel dietary supplement. J Food Nutr Disor. 2013;2(1):1-6.

2. Jugdaohsingh R et al. Dietary Silicon Intake is Positively Associated with Bone Mineral Density in Men and Premenopasual Women of the Framingham Offspring Cohort. J Bone Miner Res. 2004;19(2):297-307.
3. Arjmandi BH, Khalil DA, Lucas EA, et al. Dried plums improve indices of bone formation in postmenopausal women. J Womens Health Gend Based Med. 2002 Jan;11(1):61-8.
4. Bu SY, Lerner M, Stoecker BJ, et al. Dried plum polyphenols inhibit osteoclastogenesis by downregulating NFATc1 and inflammatory mediators. Calcif Tissue Int. 2008 Jun;82(6):475-88.
5. Franklin M, Bu SY, Lerner MR, et al. Dried plum prevents bone loss in a male osteoporosis model via IGF-I and the RANK pathway. Bone. 2006 Dec;39(6):1331-42.
6. Bu SY, Hunt TS, Smith BJ. Dried plum polyphenols attenuate the detrimental effects of TNF-alpha on osteoblast function coincident with up-regulation of Runx2, Osterix and IGF-I. J Nutr Biochem. 2009 Jan;20(1):35-44.
7. Bu SY, Lucas EA, Franklin M, et al. Comparison of dried plum supplementation and intermittent PTH in restoring bone in osteopenic orchidectomized rats. Osteoporos Int. 2007 Jul;18(7):931-42.
8. Deyhim F, Stoecker BJ, Brusewitz GH, Devareddy L, Arjmandi BH. Dried plum reverses bone loss in an osteopenic rat model of osteoporosis. Menopause. 2005 Nov;12(6):755-62.

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